Pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides...

C - Chemistry – Metallurgy – 07 – D

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C07D 413/14 (2006.01) A61K 31/53 (2006.01) A61P 35/00 (2006.01) C07D 473/34 (2006.01) C07D 487/04 (2006.01) C07D 498/08 (2006.01)

Patent

CA 2756067

Provided herein are pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides, e.g., compounds of Formulae (IA), (IB), and (IC), and their pharmaceutical compositions, preparation, and use as agents or drugs for cancer therapy, either alone or in combination with radiation and/or other anticancer drugs.

L'invention concerne des pyrimidinyl et 1,3,5-triazinyl benzimidazole sulfonamides, par exemple des composés de formules (IA), (IB) et (IC), et leurs compositions pharmaceutiques, leur préparation et leur utilisation comme agents ou médicaments de thérapie anticancéreuse, seuls ou en combinaison avec une irradiation et/ou d'autres médicaments anticancéreux.

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