C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2578630
Compounds of formula (I) possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. The invention features a compound of the general formula (I) and uses thereof.
Les composés représentés par la formule (I) possèdent de manière inattendue une haute affinité pour Alk 5 et/ou pour Alk 4 et peuvent convenir comme antagonistes de ceux-ci pour prévenir et/ou traiter de nombreuses maladies, notamment des troubles fibrotiques. Cette invention concerne les composés représentés par la formule (I) et des utilisations de ceux-ci.
Chuaqui Claudio
Lee Wen-Cherng
Shan Feng
Singh Juswinder
Sun Lihong
Biogen Idec Ma Inc.
Gowling Lafleur Henderson Llp
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