Pyrimido [5,4-d] pyrimidine derivatives for the inhibition...

Details Pyrimido [5,4-d] pyrimidine derivatives for the inhibition... Pyrimido [5,4-d] pyrimidine derivatives for the inhibition...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/40 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2752265

The present invention encompasses compounds of general formula (1), wherein the groups R1 to R4, X1, V2, V3, X4, X5, Q, L1 and L2 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, as well as pharmaceutical preparations and formulations of these compounds.

La présente invention concerne des composés de formule générale (1), dans laquelle les groupes R1 à R4, X1, X2, X3, X4, X5, Q, L1 et L2 sont tels que définis dans la revendication 1, lesdits composés étant appropriés pour le traitement de maladies caractérisées par une prolifération cellulaire excessive ou anormale, ainsi que des préparations et des formulations pharmaceutiques de ces composés.

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