Pyrimidones

C - Chemistry – Metallurgy – 07 – D

Patent

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260/254, 260/242

C07D 239/91 (2006.01) C07D 213/82 (2006.01) C07D 265/22 (2006.01) C07D 471/04 (2006.01) C07D 498/04 (2006.01)

Patent

CA 1217767

ABSTRACT: Pyrimidones Pyrimidones of general formula (I) Image wherein A and B together with the carbon atoms to which they are attached, represent an optionally substituted phenyl ring or a pyridine ring; D represents an alkylene or hydroxyalkylene group; R3 and R5 each represents a hydrogen atom or an alkyl group; R4 represents a hydrogen atom or an alkoxy group; and R6 represents an alkyl group or an alkylene or hydroxy- alkylene group substituted by an optionally substituted phenyl or phenoxy group; and their salts, which show interesting pharmacological properties, especially hypotensive, antiarrhythmic and .beta.-receptor-blocking activities.

392067

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