C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/10 (2006.01) A61K 31/438 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) C07D 487/10 (2006.01)
Patent
CA 2714888
The present invention provides compounds of Formula (I) including tautomers, resolved enantiomers, resolved diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as Akt protein kinase inhibitors and for the treatment of Akt-mediated diseases, for example, hyperproliferative diseases such as cancer.
L'invention concerne des composés de formule (I) y compris les tautomères, énantiomères résolus, diastéréoisomères résolus, solvates, métabolites, sels et promédicaments pharmaceutiquement acceptables de ceux-ci. Il est également proposé des procédés d'utilisation des composés de la présente invention en tant qu'inhibiteurs de protéine kinase Akt pour le traitement de maladies véhiculées par Akt, par exemple des maladies hyperprolifératives telles que le cancer.
Banka Anna
Bencsik Josef R.
Blake James F.
Fong Kin Chiu
Hentemann Martin F.
Array Biopharma Inc.
Banka Anna
Bencsik Josef R.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Blake James F.
LandOfFree
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