Pyrimidyl sulphone amide derivatives as chemokine receptor...

Details Pyrimidyl sulphone amide derivatives as chemokine receptor... Pyrimidyl sulphone amide derivatives as chemokine receptor...

C - Chemistry, Metallurgy

07

D

C07D 239/48 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61P 11/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 239/69 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2493785

A compound of formula (I), pharmaceutically acceptable salt, solvate or in vivo hydrolysable ester thereof for the treatment of asthma, allergic rhinitis, COPD, inflammatory bowel disease, irritable bowel syndrome, osteoarthritis, osteoporosis, rheumatoid arthritis, psoriasis or cancer.

La présente invention concerne un composé représenté par la formule générale (I), l'un de ses sels, solvates ou esters hydrolysables in vivo, pharmaceutiquement admis. Ces composés conviennent particulièrement au traitement de l'asthme, de rhinite allergique, de bronchopneumopathie chronique obstructive, de maladie intestinale inflammatoire, de syndrome de côlon irritable, d'ostéoarthrite, d'ostéoporose, de polyarthrite rhumatoïde, de psoriasis ou de cancer.

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