Pyrine or pyrazine derivatives for treating hcv

Details Pyrine or pyrazine derivatives for treating hcv Pyrine or pyrazine derivatives for treating hcv

C - Chemistry, Metallurgy

07

D

C07D 405/02 (2006.01) A61K 31/4427 (2006.01) A61K 31/5377 (2006.01) A61P 31/14 (2006.01) C07D 401/02 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2736472

Compounds having the formula I wherein R1, R2a, R2b, R2c, R3, Y and p are as defined herein and C2-C3 is a single or double bond are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.

Linvention concerne des composés de formule I, dans laquelle R1, R2a, R2b, R2c, R3, Y et p sont tels que définis dans le présent document et C2-C3 est une simple ou double liaison, qui sont des inhibiteurs de NS5b polymérase du virus de lhépatite C. Linvention concerne également des compositions et des procédés de traitement dune infection par le VHC et dinhibition de la réplication du VHC.

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