Pyrones as inhibitors of cyclooxygenase-2

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 309/38 (2006.01) A61K 31/35 (2006.01)

Patent

CA 2412874

The invention encompasses the novel compounds of Formula (I), which are useful in the treatment of cyclooxygenase-2 mediated diseases. The invention also encompasses certain pharmaceutical compositions comprising compounds of Formula (I) as well as methods of treating yclooxygenase-2 mediated diseases comprising administering to a patient in need of such treatment a non-toxic therapeutically effective amount of a compound of Formula (I).

Cette invention a trait à de nouveaux composés correspondant à la formule (I), qui se révèlent des plus utiles dans le traitement d'états pathologiques liés à la cyclooxygénase-2. Elle concerne également certaines compositions pharmaceutiques comportant des composés correspondant à la formule (I) ainsi que des méthodes de traitement d'états pathologiques liés à la cyclooxygénase-2, consistant à administrer au patient exigeant un tel traitement une quantité efficace du point de vue thérapeutique et non toxique d'un composé correspondant à la formule (I).

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