Pyrovalerone analogs and therapeutic uses thereof

Details Pyrovalerone analogs and therapeutic uses thereof Pyrovalerone analogs and therapeutic uses thereof

C - Chemistry, Metallurgy

07

D

C07D 207/06 (2006.01)

Patent

CA 2542077

New compounds that bind to monoamine transporters are described. The compounds of the present invention can be racemic or pureR-or S-enantiomers. Certain preferred compounds of the present invention have a high selectively dopamine transporter versus the serotonin transporter. Preferred monoamine transporters for the practice of the present invention include the dopamine transporter, the serotonin transporter and the norepinephrine transporter.

L'invention concerne des composés qui se lient avec des transporteurs de monoamine. Ces composés peuvent être des R- ou S-énantiomères racémiques ou purs. De préférence, certains ont une sélectivité élevée pour le transporteur de dopamine par rapport au transporteur de sérotonine. Les transporteurs de monoamine préférés pour les besoins de l'invention sont le transporteur de dopamine, le transporteur de sérotonine et le transporteur de norépinéphrine.

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