Pyrrol derivatives, preparation and use of the same in therapy

Details Pyrrol derivatives, preparation and use of the same in therapy Pyrrol derivatives, preparation and use of the same in therapy

C - Chemistry, Metallurgy

07

D

C07D 207/06 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) C07D 211/06 (2006.01) C07D 211/66 (2006.01) C07D 241/04 (2006.01) C07D 317/58 (2006.01) C07D 401/06 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2669996

The invention relates to compounds having the formula (I), wherein A represents: a substituted or non substituted alkylene (C1-C6) group; a Formula (II) group having m = O, 1 or 2 and p = 0 or 1; R1 represents hydrogen or a (C1 -C2 )alkyl; R2 represents a substituted or non substituted (C3-C10) alkyl group, a substituted or non substituted non aromatic (C3-C12) carbocylic radical, a heterocyclic substituted or non substituted radical, an alkylene (C1-C3) substituted group, a NR10R11 group; R9 represents a functional group or a heterocyclic radical. Preparation method and use in therapy.<0}

L'invention a pour objet des composés répondant à la formule (I) dans laquelle A représente : un groupe alkylène en (C1-C6) non substitué ou substitué; un groupe Formule (II) avec m = 0, 1 ou 2 et p = 0 ou 1; R1 représente l'hydrogène ou un (C1 -C4 )alkyle; R2 représente : un groupe (C3-C10)alkyle non substitué ou substitué; un radical carbocyclique non aromatique en C3-C12) non substitué ou substitué; un radical hétérocyclique non substitué ou substitué; un groupe (C1-C3)alkylène substitué; un groupement NR10R11; R9 représente un groupe fonctionnel ou un radical hétérocyclique; Procédé de préparation et application en thérapeutique.

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