C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/325 (2006.01) A61K 31/402 (2006.01) A61P 25/28 (2006.01) C07D 207/33 (2006.01) C07D 207/34 (2006.01)
Patent
CA 2623558
Novel pyrrole derivatives are disclosed as A.beta. 42-lowering agents for the treatment and prevention of neurodegenerative disorders characterized by the formation or accumulation of amyloid plaques comprising the A.beta. 42 peptide.
L'invention concerne de nouveaux dérivés de pyrroles utilisés en tant qu'agents réducteurs d'Aß42 dans le traitement et la prévention de troubles neurodégénératifs, caractérisés en ce que des plaques amyloïdes comprenant le peptide A.beta.42 sont formées ou accumulées.
Anderson Mark B.
Klimova Yevgeniya I.
Slade Rachel M.
Walton Ruth J.
Weiner Warren S.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Myriad Genetics Inc.
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