Pyrrolidin-3-yl compounds useful as beta-secretase...

Details Pyrrolidin-3-yl compounds useful as beta-secretase... Pyrrolidin-3-yl compounds useful as beta-secretase...

C - Chemistry, Metallurgy

07

D

C07D 207/14 (2006.01)

Patent

CA 2570995

The present invention is directed to pyrrolidin-3-yl derivative compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.

L'invention concerne des composés de dérivés pyrrolidin-3-yle qui sont des inhibiteurs de l'enzyme bêta-secrétase et qui sont utiles dans le traitement de maladies, telles que la maladie d'Alzheimer, dans lesquelles cette dernière est impliquée. L'invention porte également sur des compositions pharmaceutiques comprenant ces composés, sur l'utilisation de ces composés et compositions dans le traitement des maladies dans lesquelles la bêta-secrétase est impliquée.

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