Pyrrolidin-3-ylmethyl-amine as orexin antagonists

C - Chemistry – Metallurgy – 07 – D

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C07D 403/12 (2006.01) A61K 31/423 (2006.01) A61P 25/00 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2731403

The present invention is concerned with compounds of formula (I) wherein R1, R2, Ar, Hetaryl, m and n are as de-scribed in the description and claims. The compounds are orexin receptor antagonists may be useful in the treatment of disorders, in which orexin pathways are involved.

La présente invention porte sur des composés de formule (I), dans laquelle R1, R2, Ar, Hetaryl, m et n sont tels que définis dans la description et les revendications. Les composés sont des antagonistes des récepteurs de l'orexine, qui peuvent être utiles pour le traitement daffections dans lesquelles les voies de l'orexine sont impliquées.

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