Pyrrolidine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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260/317, 71/8.5

C07D 209/02 (2006.01) A01N 43/38 (2006.01) C07D 209/52 (2006.01)

Patent

CA 1124722

ABSTRACT A process for the conversion of the trans isomer of an acid whose carbon skeleton includes the unit (I) Image or a salt, ester, or salt of an ester, thereof, into the cis isomer of such a compound which comprises converting the trans isomer into an acid whose carbon skeleton includes the unit Image (II) or a salt thereof, and subsequently hydrogenating said compound and, in the event of an ester or salt thereof being required converting the resulting free acid or salt thereof into the required ester or salt thereof. The compound 2-carboxy-3-aza- bicyclo[3.1.0]hex-2-ene or a salt and/or amide, alkylamide, hydrazide or alkylhydrazide thereof may be used as a pollen suppressant.

364014

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