C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/323, 260/306
C07D 409/04 (2006.01) C07D 207/08 (2006.01) C07D 333/04 (2006.01)
Patent
CA 1095918
ABSTRACT These are described novel pyrrolidine derivatives of the general formula Image (I) , wherein R1 represents the 2-thienyl group or a phenyl group substituted by a lower tertiary amino group, R2 and R3 each independently represent a hydrogen atom or a lower alkyl group and R4 represents a phenyl group which may be substituted by halogen, lower alkyl, lower alkoxy, nitro or primary, lower secondary or lower tertiary amino, with the proviso that R1 represents a phenyl group substituted by a lower tertiary amino group when R4 represents a phenyl or halo- -substituted phenyl group, and acid addition salts thereof which show analgesic activity without being addictive.
283401
Bernauer Karl
Pfoertner Karlheinz
Schmid Hans E.
Schneider Fernand
Gowling Lafleur Henderson Llp
Hoffmann-La Roche Limited
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