Pyrrolidine derivatives acting as ccr3-receptor antagonists

Details Pyrrolidine derivatives acting as ccr3-receptor antagonists Pyrrolidine derivatives acting as ccr3-receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 207/12 (2006.01) A61K 31/4015 (2006.01) A61P 11/06 (2006.01)

Patent

CA 2552928

Compounds of formula (I) in free or salt form, wherein T, X, Y, U, R1, R2, m, n and p have the meanings as indicated in the specification, are useful for treating conditions mediated by CCR3. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.

L'invention se rapporte à des composés de formule (I) sous forme libre ou sous forme de sel, qui peuvent servir à traiter des états dont la médiation est assurée par le récepteur CCR3. Dans ladite formule (I), T, X, Y, U, R?1¿, R?2¿,? ¿m, n et p sont tels que définis dans la description. Cette invention concerne en outre des compositions pharmaceutiques qui contiennent ces composés, ainsi que des procédés pour préparer lesdits composés.

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