Pyrrolidine derivatives as ccr5 antagonists

Details Pyrrolidine derivatives as ccr5 antagonists Pyrrolidine derivatives as ccr5 antagonists

C - Chemistry, Metallurgy

07

D

C07D 401/06 (2006.01) A61K 31/4025 (2006.01) A61K 31/435 (2006.01) A61P 1/00 (2006.01) A61P 17/00 (2006.01) A61P 19/00 (2006.01) A61P 31/18 (2006.01) C07D 403/08 (2006.01) C07D 413/08 (2006.01)

Patent

CA 2569861

The present invention discloses the compounds of formula I or their pharmaceutically acceptable salts, which are useful as CCR5 antagonists. The preparation and use of the compounds of formula I, pharmaceutical composition containing the same are also disclosed. Furthermore, the present invention discloses an intermediate for the preparation of the compounds of formula I.

Cette invention concerne des composés représentés par la formule (I) ou leurs sels acceptables sur le plan pharmaceutique, qui sont utiles comme antagonistes de CCR5. La préparation et l'utilisation de ces composés de formule (I) et une composition pharmaceutique contenant ces composés sont également décrites. Cette invention concerne en outre un intermédiaire pour la préparation de ces composés de formule (I).

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