Pyrrolidine derivatives having activity at the glyt1...

Details Pyrrolidine derivatives having activity at the glyt1... Pyrrolidine derivatives having activity at the glyt1...

C - Chemistry, Metallurgy

07

D

C07D 207/06 (2006.01) A61K 31/401 (2006.01) A61P 25/18 (2006.01)

Patent

CA 2655399

The succinate and napadisylate salts and solvates of 2-(Methyloxy)-/V-[2-methyl-1-phenyl-2- (1-pyrrolidinyl)propyl]-4,6-bis(trifluoromethyl)benzamide,6-bis(trifluoromethyl)benzamide napadisylate, and uses thereof in the treatment of disorders relating to GIyT1 transporter, such as schizophrenia, are disclosed.

La présente invention concerne des sels et des solvates de succinate et de napadisylate de 2-(méthyloxy)-N-[2-méthyl-1-phényl-2-(1-pyrrolidinyl)propyl]-4,6-bis(trifluorométhyl)benzamide, le napadisylate de 6-bis(trifluorométhyl)benzamide et leurs utilisations dans le traitement des troubles liés au transporteur GlyT1, tels que la schizophrénie.

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