Pyrrolidine inhibitors of iap

Details Pyrrolidine inhibitors of iap Pyrrolidine inhibitors of iap

C - Chemistry, Metallurgy

07

D

C07D 417/04 (2006.01) A61K 31/427 (2006.01) A61P 35/00 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2588921

The invention provides novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies where the compounds have the general formula (I), wherein A,Q,X1,X2,Y,R1,R2,R3,R4,R4~,R5,R6 and R6~ are described herein.

La présente invention concerne de nouveaux inhibiteurs des IAP qui peuvent être utilisés comme agents thérapeutiques dans le traitement des tumeurs malignes. Ces composés correspondent à la formule générale (I) dans laquelle A, Q, X1, X2, Y, R1, R2, R3, R4, R4~, R5, R6 et R6' sont décrits dans l'invention.

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