Pyrrolidinyl and piperidinyl compounds useful as nhe-1...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 207/09 (2006.01) C07D 211/34 (2006.01) C07D 211/82 (2006.01) C07D 401/10 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 405/10 (2006.01) C07D 405/14 (2006.01) C07D 407/06 (2006.01) C07D 409/06 (2006.01) C07D 413/06 (2006.01) C07D 413/10 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2730116

Disclosed are compounds of formula (I) and compositions of the present invention which are inhibitors of the sodi-um proton exchanger isoform-1 (NHE-I). Also disclosed are methods of using and making the same.

L'invention porte sur des composés et des compositions qui sont des inhibiteurs de l'isoforme-1 de l'échangeur sodium-proton (NHE-1). L'invention porte également sur des procédés d'utilisation et de fabrication de ceux-ci.

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