C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/233, 260/325
C07D 295/192 (2006.01) A61K 31/40 (2006.01)
Patent
CA 1280428
NOVEL PYRROLIDINYLAMIDE ESTER DERIVATIVE HAVING ANTI-PROLYL ENDOPEPTIDASE ACTIVITY AND SYNTHESIS AND USE THEREOF Abstract A novel pyrrolidinylamide ester derivative that exhibits inhibitory activity against prolyl endopeptidase, methods for synthesis thereof and its use as an inhibitor against said enzyme are disclosed. The pyrrolidinylamide ester of the invention has the following general formula: Image wherein n is o or an lnteger or 1 to 7 and R is hydrogen atom or a straight or branched alkyl having 1 to 8 carbon atoms.
523852
Fukami Harukazu
Hashimoto Masaki
Higuchi Naoki
Saitoh Masayuki
Tanaka Takaharu
Suntory Limited
Swabey Ogilvy Renault
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