Pyrrolidone-2 compounds and their use for central analgesic...

C - Chemistry – Metallurgy – 07 – D

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C07D 207/27 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/445 (2006.01) C07D 207/26 (2006.01) C07D 211/76 (2006.01) C07D 409/06 (2006.01) C07D 413/06 (2006.01)

Patent

CA 1336333

Compounds of formula Image (I) (wherein R, R1, R2, R3 and n have the meanings reported in the specification), their salts with pharmaceutically acceptable acids, process for their preparation and pharmaceutical composi- tions containing them are described. The compounds of formula I have a remarkable analgesic activity.

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