Pyrrolidone derivatives as maob inhibitors

Details Pyrrolidone derivatives as maob inhibitors Pyrrolidone derivatives as maob inhibitors

C - Chemistry, Metallurgy

07

D

C07D 207/26 (2006.01) A61K 31/4015 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) C07D 207/273 (2006.01) C07D 207/277 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2496756

Racemic enantiomerically pure 4- pyrrolidino derivatives of formula (I), processes for their preparation, pharmaceutical compositions comprising said derivatives, and their use in the prevention and treatment of illness, in particular which is mediated by monoamine oxidase B inhibitors, in particular Alzheimer~s disease or senile dementia.

L'invention concerne des dérivés racémiques 4-pyrrolidino énantiomériquement purs de la formule (I), leurs procédés de préparation, des compositions pharmaceutiques comprenant ces dérivés et leur utilisation dans la prévention et le traitement de maladies, en particulier de maladies induites par les inhibiteurs de la monoamine-oxydase de type B, et plus précisément de la maladie d'Alzheimer ou de la démence sénile.

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