Pyrrolidone derivatives as maob inhibitors

Details Pyrrolidone derivatives as maob inhibitors Pyrrolidone derivatives as maob inhibitors

C - Chemistry, Metallurgy

07

D

C07D 207/26 (2006.01) C07D 207/273 (2006.01) C07D 207/277 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2498785

Racemic or enantiomerically pure 4-pyrrolidino derivatives of the formula (I), processes for their preparation, pharmaceutical compositions comprising said derivatives, and their use in the prevention and treatment of a disease which is mediated by a monoamine oxidase B inhibitor, in particular Alzheimer's disease and senile dementia.

L'invention concerne des dérivés de 4-pyrrolidino racémiques ou énantiomériquement pures de formule (I), leurs procédés de préparation, des compositions pharmaceutiques comprenant ces dérivés, et leur utilisation dans la prévention et le traitement d'une maladie qui est régulée par un inhibiteur de la monoamine oxydase B, en particulier la maladie d'Alzheimer et la démence sénile.

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