Pyrrolizidine compounds, methods for their production, and...

Details Pyrrolizidine compounds, methods for their production, and... Pyrrolizidine compounds, methods for their production, and...

C - Chemistry, Metallurgy

07

D

167/233, 260/299

C07D 487/04 (2006.01) A61K 31/40 (2006.01)

Patent

CA 1255681

Abstract: Pyrrolizidine compounds, methods for their production, and their uses A novel pyrrolizidine compound of the formula Image (wherein R1 is an alkyl group of 1 to 4 carbon atoms or a pheyl group; and R2 and R3 are such that at least one of them is an alkyl group of 1 to 4 carbon atoms with the other, if any, being a hydrogen atom) is produced by reacting .DELTA.4(8)-dehydropyrrolizidine with a sub- stituted malonic acid and thus formed 2-substituted-8-pyrrol- izidineacetic acid with a substituted aniline. The product is optionally subjected to optical resolution. The pyrrolizid- ine compound has more potent antiarrhythmic activity than known similar pyrrolizidine compounds.

486237

Affiliated with

Also associated with

Rating

Pyrrolizidine compounds, methods for their production, and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pyrrolizidine compounds, methods for their production, and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrrolizidine compounds, methods for their production, and... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1210462