Pyrrolo[1,2-a]imidazoledione effective in the treatment of...

A - Human Necessities – 61 – K

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A61K 31/4188 (2006.01) A61P 25/02 (2006.01) A61P 39/00 (2006.01)

Patent

CA 2669853

The use of a compound of formula (I), is disclosed in treating and/or preventing 5 chemotherapy-induced peripheral neurotoxicity (CIPN). The invention includes pharmaceutical compositions wherein the compound of formula (I) is present in a mixture with anticancer agents. An improved anticancer treatment with reduced CIPN-related side effects is also provided.

La présente invention concerne l'utilisation d'un composé de formule (I) capable de traiter et/ou de prévenir la neurotoxicité périphérique induite par la chimiothérapie (CIPN). L'invention inclut des compositions pharmaceutiques contenant le composé de formule (I) dans un mélange avec des agents anticancéreux. L'invention concerne également un traitement anticancéreux amélioré avec des effets secondaires CIPN réduits.

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