Pyrrolo¬1,2-b|¬1,2,5|triazepines, a process and...

Details Pyrrolo¬1,2-b|¬1,2,5|triazepines, a process and... Pyrrolo¬1,2-b|¬1,2,5|triazepines, a process and...

C - Chemistry, Metallurgy

07

D

260/238.1

C07D 487/04 (2006.01) C07D 207/50 (2006.01)

Patent

CA 1251790

ABSTRACT Pyrrolo[1,2-b][1,2,5]triazepines There are described novel pyrrolo[1,2-b][1,2,5]triazepines of the general formula Image (I) where R is hydrogen, loweralkyl, loweralkylaminoloweralkyl or diloweralkylaminoloweralkyl; X is hydrogen, halogen trifluoromethyl or nitro; and Y is hydrogen, halogen or loweralkyl. Also described are derivatives of 1-amino-2- benzoylpyrrole having the general formula Image (II) where R, X and Y are as defined above End R1 is hydrogen, Image Image Compounds I and II are useful as analgesic, anxiolytic and/or anticonvulsant agents, and many of Compounds II are useful as intermediates for synthesizing Compounds I. - 2 -

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