Pyrrolo[2,1-b]thiazole derivatives

Details Pyrrolo[2,1-b]thiazole derivatives Pyrrolo[2,1-b]thiazole derivatives

C - Chemistry, Metallurgy

07

D

167/211, 167/234

C07D 513/04 (2006.01) A61K 31/395 (2006.01) C07D 207/24 (2006.01) C07D 207/36 (2006.01)

Patent

CA 2021135

ABSTRACT A novel compound represented by the following formula (I): Image (I) wherein R1 represents a hydrogen atom, an alkyl group or a cyclic alkyl group; R2 represents a hydroxyl group, an alkoxy group which may have one to three substituents in the alkyl group moiety, an arylthio group which may have one or more substituents in the aryl group moiety, an aryloxy group which may have one or more substituents in the aryl group moiety, an amino group, an alkylamino group or a cyclic amino group which may contain other hetero atoms as ring atoms selected from a nitrogen atom, an oxygen atom and a sulfur atom; R3 represents a hydrogen atom, an alkyl group, an aryl group which may have one or more substituents, or a hetero aryl group which may have one or more substituents; and ----- represents a single bond or a double bond; salts thereof, and pharmaceutical preparations for preventing and treating hepatic diseases containing the compound of the formula (I) or salts thereof as an active ingredient are disclosed.

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