Pyrrolo¬2,3-b|indole-ketones and analogs, a process for...

Details Pyrrolo¬2,3-b|indole-ketones and analogs, a process for... Pyrrolo¬2,3-b|indole-ketones and analogs, a process for...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2042327

This invention relates to pyrrolo[2,3-b]indole ketones of the formula see formula I where R1 is loweralkyl, aryl or arylloweralkyl; R2 is hydrogen, halogen or loweralkyl; R3 is hydrogen or loweralkyl; R4 is loweralkyl or arylloweralkyl; R5 is hydrogen, loweralkyl, loweralkenyl, loweralkynyl, arylloweralkyl, formyl, loweralkylcarbonyl, arylloweralkylcarbonyl or loweralkoxycarbonyl; Y is hydrogen, halogen, loweralkyl or loweralkoxy; the pharmaceutically acceptable addition salts thereof, and where applicable, the geometric and optical isomers and racemic mixtures thereof. The compounds of this invention exhibit utility for alleviating various memory dysfunctions such as Alzheimers disease.

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