Pyrrolo[2,3-d]pyrimidin-2-yl-amine derivatives as pkc-theta...

Details Pyrrolo[2,3-d]pyrimidin-2-yl-amine derivatives as pkc-theta... Pyrrolo[2,3-d]pyrimidin-2-yl-amine derivatives as pkc-theta...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2716202

The present invention relates to a pyrrolo[2,3-d]pyrimidin-2-yl-amine derivative according to formula (I) wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising one or more of said pyrrolo[2,3-d]pyrimidine-2-ylamine derivatives and to their use in therapy, for instance in the treatment of PKC9 mediated disorders.

La présente invention porte sur un dérivé de pyrrolo[2,3-d]pyrimidin-2-ylamine selon la formule (I) dans laquelle les variables sont telles que définies dans la description, ou sur un sel pharmaceutiquement acceptable ou solvate de celui-ci. La présente invention porte également sur une composition pharmaceutique comprenant un ou plusieurs desdits dérivés de pyrrolo[2,3-d]pyrimidin-2-ylamine et sur leur utilisation en thérapie, par exemple dans le traitement de troubles facilités par PKC?.

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