Pyrrolo[2,3-d]pyrimidine derivatives; their intermediates...

Details Pyrrolo[2,3-d]pyrimidine derivatives; their intermediates... Pyrrolo[2,3-d]pyrimidine derivatives; their intermediates...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) C07D 211/56 (2006.01)

Patent

CA 2614907

This invention relates to methods and intermediates useful for the synthesis of pyrrolo [2,3-d] pyrimidine compounds. Specifically novel synthetic methods and intermediates for the synthesis of 3- {(3R, 4R)-4-methyl-(7H-pyrrolo[2,3-d] pyrimidin-4-yl)-amino}-piperidin-1-yl)-3-oxo-propionitrile and its corresponding citrate salt are disclosed.

La présente invention a trait à des procédés et des intermédiaires utiles pour la synthèse de composés pyrrolo [2,3-d] pyrimidine. De manière spécifique l'invention a trait à de nouveaux procédés de synthèse et des intermédiaires pour la synthèse de 3- {(3R, 4R)-4-méthyl-(7H-pyrrolo[2,3-d] pyrimidin-4-yl)-amino}-pipéridin-1-yl)-3-oxo-propionitrile et son sel citrate correspondant.

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