Pyrrolo[2,3-d]pyrimidines that modulate ack1 and lck activity

Details Pyrrolo[2,3-d]pyrimidines that modulate ack1 and lck activity Pyrrolo[2,3-d]pyrimidines that modulate ack1 and lck activity

C - Chemistry, Metallurgy

07

D

C07D 487/00 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2572314

Compounds that modulate the action of ACK1 and LCK, and related compositions methods for treating ACK1- and LCK-mediated diseases are described. In one aspect, the compounds have the general structure: where the values of the substituents are provided herein.

Cette invention concerne des composés qui modulent l'action de ACK1 et de LCK, ainsi que des compositions et des méthodes connexes convenant pour le traitement des maladies induites par ACK1 et LCK. Selon un aspect de l'invention, les composés présentent la structure générale suivante: (I) dans laquelle les valeurs des substituants sont indiquées dans le descriptif.

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