Pyrrolo (3,4-c) carbazole and pyrido (2,3-b) pyrrolo (3,4-e)...

Details Pyrrolo (3,4-c) carbazole and pyrido (2,3-b) pyrrolo (3,4-e)... Pyrrolo (3,4-c) carbazole and pyrido (2,3-b) pyrrolo (3,4-e)...

C - Chemistry, Metallurgy

07

D

C07D 471/22 (2006.01) A61K 31/407 (2006.01) A61K 31/437 (2006.01) A61P 35/00 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01) C07D 487/14 (2006.01)

Patent

CA 2502515

The invention concerns compounds of formula (I), wherein: Z represents a group of formula U-V such as defined in the description; W¿1? represents, with the carbon atoms to which it is bound, a phenyl group or a pyridinyl group; W¿2? is such as defined in the description; X¿1?, X¿2? represent each a hydrogen atom, a hydroxy, alkoxy, mercapto or alkylthio group; Y¿1?, Y¿2? represent each a hydrogen atom, or X¿1? and Y¿1?, X¿2? and Y¿2? represent each a hydrogen atom, a hydroxy, a linear or branched C¿1?-C¿6? alkoxy, mercapto, and linear or branched C¿1?-C¿6? alkythio group; R¿1? is such as defined in the description; Q represents an oxygen atom or a NR¿2? group such as defined in the description.

Composés de formule (I): dans laquelle: Z représente un groupement de formule U-V telle que définie dans la description, W1 représente, avec les atomes de carbone auxquels il est lié, un groupement phényle ou un groupement pyridinyle, W2 est tel que défini dans la description, X1, X2 représentent chacun un atome d'hydrogène, un groupement hydroxy, alkoxy, mercapto ou alkylthio, Y1, Y2 représentent chacun un atome d'hydrogène, ou X1 et Y1, X2 et Y2 représentent chacun un groupement choisi parmi atome d'hydrogène, groupement hydroxy, alkoxy (C1-C6) linéaire ou ramifié, mercapto, et alkylthio (C1-C6) linéaire ou ramifié, R1 est tel que défini dans la description, Q représente un atome d'oxygène ou un groupement NR2 tel que défini dans la description.

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