Pyrrolo[3,4-c]pyrazole derivatives active as kinase inhibitors

Details Pyrrolo[3,4-c]pyrazole derivatives active as kinase inhibitors Pyrrolo[3,4-c]pyrazole derivatives active as kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/4162 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2531759

Pyrrolo[3,4-c]pyrazole derivatives of formula (1) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.

L'invention porte: sur des dérivés du pyrrolo[3,4-c]pyrazole de formule (I) et leurs sels pharmacocompatibles, tels que définis dans la spécification; sur leur procédé de préparation; et sur des préparations pharmaceutiques les comprenant. Lesdits composés peuvent servir en thérapie au traitement de maladies, associées à un dérèglement de l'activité des protéines kinases, telles que le cancer.

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