Pyrrolo¬3,4-d|pyrimidines as corticotropin releasing factor...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) A61K 31/505 (2006.01) C07D 209/00 (2006.01) C07D 239/00 (2006.01)

Patent

CA 2413651

Corticotropin releasing factor (CRF) antagonists of Formula (I) or (II) and their use in treating anxiety, depression, and other psychiatric, neurological disorders as well as treatment of immunological, cardiovascular or heart- related diseases and colonic hypersensitivity associated with psychopathological disturbance and stress.

L'invention concerne des antagonistes de corticolibérine (CRF) représentés par la formule (I) ou (II) et leur utilisation dans le traitement de l'angoisse, de la dépression et d'autres troubles mentaux, neurologiques, ainsi que dans le traitement de maladies immunologiques, cardiovasculaires ou de cardiopathies et de l'hypersensibilité du côlon associée à l'agitation et au stress psychopathologiques.

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