Pyrrolo-dibenzo-oxazepines, thiazepines and azepines

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 1082182

Title: Amino-substituted tetracyclic compounds Abstract of the Disclosure The invention is dealing with compounds of the general formula: Image as well as the pharmaceutically acceptable salts thereof, in which X represents oxygen, sulphur, the group ?NR7 or the group -CR8R9-, R1, R2, R3 and R4 represent hydrogen, hydroxy, halogen, an alkyl, alkoxy or alkylthio group or a trifluoromethyl group, R5 and R6 represent hydrogen, an alkyl group or an aralkyl group, R7 represents hydrogen or alkyl (1-4 C), R8, R9 represent hydrogen or methyl, and Q represents hydrogen (2H) or oxygen, having valuable antihistamine, sedative and antidepressive properties.

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