C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/551 (2006.01) A61P 31/00 (2006.01)
Patent
CA 2543318
Disclosed are compounds of Formula (I) wherein X, Y, R1-R7, T1, T2, Z, and p are as described herein; a pharmaceutical composition comprising a compound of Formula (I) and a carrier; a method of inhibiting growth of a cell, which method comprises administering in an amount effective to inhibit growth a compound of Formula (I); a method of treating cancer in a mammal, which method comprises administering in an amount effective to treat cancer a compound of Formula (I); a method of treating a viral, parasitic, or bacterial infection of a cell, which method comprises administering in an amount effective to treat a viral, parasitic, or bacterial infection a compound of Formula (I); and a method of preparing a compound of Formula (I) as described herein.
L'invention concerne des composés de formule (I), dans laquelleX, Y, R1-R7, T1, T2, Z et p sont tels que décrits dans le mémorandum descriptif. Elle concerne une composition pharmaceutique comprenant un composé de formule (I) et un support. Elle concerne en outre une méthode pouvant inhiber la croissance d'une cellule par administration d'une quantité efficace d'un composé de formule (I); une méthode de traitement du cancer chez un mammifère par administration d'une quantité efficace d'un composé de formule (I); une méthode de traitement d'une infection virale, parasitaire ou bactérienne d'une cellule par administration d'une quantité efficace d'un composé de formule (I); et une méthode de préparation d'un composé de formule (I).
Howard Philip W.
Hsiao Luke Y.
Liu Paul S.
Rao Vishnuvajjala B.
Snader Kenneth M.
Government Of The United States Of America As Representated By T
Midwest Research Institute
Ridout & Maybee Llp
Spirogen Ltd.
Starks Associates Inc.
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