Pyrrolopyrazinyl urea kinase inhibitors

Details Pyrrolopyrazinyl urea kinase inhibitors Pyrrolopyrazinyl urea kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/4985 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2744507

The present invention relates to the use of novel pyrrolopyrazinyl urea derivatives of Formula (I), wherein the variables R1, R2 , R3, R4, and R5 are defined as described herein, which inhibit JAK and are useful for the treatment of auto-immune and inflammatory diseases.

La présente invention concerne l'emploi de nouveaux dérivés de pyrrolopyrazinylurée de Formule (I), où les variables R1, R2, R3, R4 et R5 sont telles que définies dans la description, lesdits dérivés inhibant JAK et pouvant être employés dans le traitement de maladies auto-immunes et inflammatoires.

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