Pyrrolopyrazoles, potent kinase inhibitors

Details Pyrrolopyrazoles, potent kinase inhibitors Pyrrolopyrazoles, potent kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 519/00 (2006.01) A61K 31/437 (2006.01) A61P 35/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2593428

Pyrrole pyrazole compounds of formula (I), compositions including these compounds and methods of their use are provided. Preferred compounds of formula I have activity as protein kinase inhibitors, including as inhibitors of PAK4.

L'invention des composés de pyrrolopyrazoles de formule (I), des compositions comprenant lesdits composés, ainsi que leurs méthodes d'utilisation. Les composés préférés de formule I présentent une activité en tant qu'inhibiteurs de protéines kinases, notamment en tant qu'inhibiteurs de PAK4.

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