C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/00 (2006.01) A61K 31/437 (2006.01) A61P 9/10 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2525502
Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are inhibitors of glycogen phosphorylase and are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, and as cardioprotectants.
L'invention concerne des composés représentés par la formule (I) et des sels de ceux-ci, acceptables d'un point de vue pharmaceutique, qui sont des inhibiteurs de la glycogène phosphorylase, et sont utiles pour le traitement prophylactique ou thérapeutique du diabète, de l'hyperglycémie, de l'hypercholestérolémie, l'hyperinsulinémie, de l'hyperlipémie, de l'hypertension, de l'athérosclérose ou de l'ischémie tissulaire par exemple l'ischémie du myocarde, et en tant que cardio-protecteurs.
Bradley Stuart Edward
Krulle Thomas Martin
Murray Peter John
Procter Martin James
Rowley Robert John
Macrae & Co.
Prosidion Limited
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