Pyrrolopyridine derivatives and their use as bace inhibitors

Details Pyrrolopyridine derivatives and their use as bace inhibitors Pyrrolopyridine derivatives and their use as bace inhibitors

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2687332

This invention relates to novel compounds having the structural formula I below: (I) and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.

La présente invention concerne de nouveaux composés représentés par la formule structurelle I ci-après : (I) et leur sel pharmaceutiquement acceptable, ainsi que des compositions et des procédés d'utilisation. Ces nouveaux composés permettent le traitement ou la prophylaxie d'une déficience cognitive, de la maladie d'Alzheimer, d'une neurodégénérescence et d'une démence.

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