Pyrrolopyridines as kinase inhibitors

Details Pyrrolopyridines as kinase inhibitors Pyrrolopyridines as kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/496 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2711614

Compounds of Formula (I) are useful for inhibition of CHK1 and/or CHK2. Methods of using compounds of Formula (I) and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.Formula, (I).

L'invention concerne des composés de formule (I) qui s'utilisent pour l'inhibition de CHK1 et/ou CKH2. Des procédés d'utilisation des composés de formule (I) et des stéréo-isomères et des sels de qualité pharmaceutique de ceux-ci, pour un diagnostic, une prévention ou un traitement in vitro, in situ et in vivo de tels troubles dans des cellules de mammifère ou d'affections pathologiques associées, sont également décrits.

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