Pyrrolopyridines useful as inhibitors of protein kinase

Details Pyrrolopyridines useful as inhibitors of protein kinase Pyrrolopyridines useful as inhibitors of protein kinase

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 35/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2609126

The present invention relates to compounds of formula (I) wherein Q, Z, R1 , R2 , and R3 are as described in claim 1 useful as inhibitors of protein kinases, particularly of JAK family and ROCK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

L'invention concerne des composés de formule (I) dans laquelle Q, Z, R1, R2, et R3 ont la signification indiquée dans la revendication 1, qui sont utiles en tant qu'inhibiteurs de protéines kinases, en particulier des kinases des familles JAK et ROCK. L'invention concerne également des compositions acceptables sur le plan pharmaceutique comprenant lesdits composés et des méthodes d'utilisation de ces compositions dans le traitement de maladies, états et troubles divers.

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