C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2546192
The invention relates to compounds of the formula (1), or a pharmaceutically acceptable salt, prodrug or hydrates thereof, wherein X, L, R1, R2, R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula (1) and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula (1).
L'invention concerne des composés de la formule (1), ou bien un de leurs sels, promédicaments ou hydrates pharmaceutiquement acceptables, X, L, R?1¿, R?2¿, R?3¿ et R?4¿ étant tels que définis dans la description. L'invention concerne également des compositions pharmaceutiques contenant les composés de la formule (1), ainsi que des méthodes de traitement des troubles hyperprolifératifs chez un mammifère par l'administration desdits composés.
Chen Jinshan
Lagreca Susan Deborah
Marx Matthew Arnold
Wessel Matthew David
Pfizer Products Inc.
Smart & Biggar
LandOfFree
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