Pyrrolopyrimidine derivatives

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 487/04 (2006.01) A61K 31/505 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2510853

The invention relates to compounds of the formula 1or a pharmaceutically acceptable salt, prodrug or hydrates thereof, wherein Q, A, L, R1, R2 and R3 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula 1.

L'invention concerne des composés de formule 1 ou un sel pharmaceutiquement acceptable, un promédicament ou des hydrates de ces derniers. Dans ladite formule Q, A, L, R?1¿, R?2¿ et R?3¿ sont tels que définis dans la description. L'invention concerne également des compositions pharmaceutiques contenant les composés de formule 1 et des méthodes de traitement de troubles hyperprolifératifs chez un mammifère par administration des composés de formule 1.

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