Pyrrolopyrimidine derivatives as syk inhibitors

Details Pyrrolopyrimidine derivatives as syk inhibitors Pyrrolopyrimidine derivatives as syk inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2625109

Pyrrolopyrimidine derivatives of formula (I) are inhibitors of Spleen Tyrosine kinase (Syk) and therefore of potential therapeutic benefit in the treatment of diseases and conditions associated with inappropriate Syk activity, in particular in the treatment of inflammatory and allergic diseases.

La présente invention concerne des dérivés de la pyrrolopyrimidine de formule (I) qui ont une activité d'inhibiteurs de la tyrosine-kinase de la rate (Syk) et qui présentent donc des avantages potentiels dans le traitement de maladies et d'états associés à une activité Syk inappropriée, en particulier des maladies inflammatoires et allergiques.

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