Pyrrolopyrimidine derivatives, their production and use

Details Pyrrolopyrimidine derivatives, their production and use Pyrrolopyrimidine derivatives, their production and use

C - Chemistry, Metallurgy

07

D

167/220, 260/242

C07D 487/04 (2006.01) A61K 31/505 (2006.01)

Patent

CA 1340794

A compound of the formula (see.formula I) wherein the ring A is a pyrrole or pyrroline ring, X is an amino group or a hydroxyl group. Y is a hydrogen atom, an amino group or a hydroxyl group, R is a hydrogen atom, a fluorine atom, an alkyl group, an alkenyl group or an alkynyl group, -COOR1 and -COOR2 are independently carboxyl groups which may be esterified and n is an integer of 2 to 4, and R may be different in each of the n repeating units, and salts thereof have excellent antitumor effects, and can be used as antitumor agents in mammals.

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