C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/505 (2006.01) A61P 19/02 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2566160
The invention relates to compounds of the formula (I) or a pharmaceutically acceptable salt, prodrug, solvate or hydrate thereof, wherein L, R', R2, R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula (I) and to methods of treating abnormal cell growth, such as cancer in a mammal by administering the compounds of formula (I).
La présente invention concerne des composés représentés par la formule générale (I) ou l'un de ses sels, promédicaments, solvates ou hydrates pharmaceutiquement admis, les R', R?2¿, R?3¿ et R?4¿ étant tels que définis dans les spécifications. L'invention concerne également des compositions pharmaceutiques contenant les composés de l'invention, ainsi que des procédés pour traiter la croissance cellulaire anormale telle que dans le cas du cancer chez un mammifère, par administration de composés de l'invention.
Arcari Joel Thomas
Chen Jinshan
La Greca Susan Deborah
Marx Matthew Arnold
Wessel Matthew David
Pfizer Products Inc.
Torys Llp
LandOfFree
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