Pyrrolopyrimidines as crf antagonists

Details Pyrrolopyrimidines as crf antagonists Pyrrolopyrimidines as crf antagonists

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) C07D 207/34 (2006.01) C07D 401/00 (2006.01) C07D 403/00 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07D 471/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2150016

The compounds of formula (I), wherein B, R3, R4, R5 and R6 are as defined herein, are useful in the treatment of stress-related and other diseases. These compounds have corticotropin-releasing factor antagonist activity and as such are of use in the treatment of depression and anxiety related, and other disorders.

Composés de la formule (I) dans laquelle B, R3, R4, R5 et R6 sont tels que définis dans le descriptif de la présente invention. Lesdits composés sont utiles dans le traitement de maladies liées au stress et d'autres maladies. Ils sont actifs comme antagonistes du facteur de libération de la corticotrophine et, à ce titre, ils sont utiles dans le traitement de la dépression, de troubles liés à l'anxiété et d'autres maladies.

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