Pyrrolopyrrolone derivatives as inhibitors of neutrophil...

Details Pyrrolopyrrolone derivatives as inhibitors of neutrophil... Pyrrolopyrrolone derivatives as inhibitors of neutrophil...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) C07D 207/14 (2006.01) C07D 207/273 (2006.01)

Patent

CA 2250209

There are described according to the invention compounds of formula (I) (relative stereochemistry indicated), wherein R1, R2, R3 and X are as defined in the specification, together with processes for preparing them, compositions containing them and their use as pharmaceuticals. Compounds of formula (I) are indicated inter alia for the treatment of chronic bronchitis.

L'invention concerne des composés selon la formule (I) (stéréochimie relative indiquée). Dans la formule, R¿1?, R¿2?, R¿3? et X sont comme définis dans le descriptif. L'invention traite également de procédés pour préparer ces composés, de compositions les contenant et de leur utilisation comme produits pharmaceutiques. Les composés de la formule (I) sont indiqués, entre autres, pour le traitement de la bronchite chronique.

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